Here’s the food item North American’s spend the most money on! Lethbridge, AB, Canada / Todays Country 95-5 Gillian Macleod July 31, 2017 06:42 am Rene Schwietzke / CC Q: What is the most profitable food item in North America? A: Pet food! Congrats Joey! You’ve won a gift certificate to the Downtown Farmer’s Market!